IPhone 4 won't sync to iTunes after 4.2.1 and snow leopard upgrade

My iPhone 4 is showing it is charging while hooked to my mac mini but will not sync. I upgraded to snow leopard and iOS 4.2.1 when I got home from vacation. Not sure which is causing the issue.
Does anyone have any trouble shooting steps I can try?
Thanks in advance for and assistance...

If not being recognized by iTunes, follow the troubleshooting steps included with this link.
http://support.apple.com/kb/TS1591

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