Iphone has gone to a screen to plug in itunes, but itunes does not recognise it

I updated the software on my iphone4 and after updating the iphone has gone to a screen to plug in itunes, but itunes does not recognise it. i have reloaded itunes, done a hard reset and still nothing. any ideas?

Gotcha,
If you have an iCloud account you might want to consider syncing that way so you won't have to use cables but that is certainly up to you.
Try:
1.) Backup all your data:
Backup your iOS device: http://support.apple.com/kb/HT1414
Backup your computer Addressbook: http://docs.info.apple.com/article.html?path=AddressBook/4.0/en/ad961.html
Backup iCal:  Click on each calendar on the left hand side of iCal one at a time highlighting it's name and then going to File Export > Export and saving the resulting calendar file to a logical location for safekeeping.
2.) Reset the computer's sync services and then restart the computer: http://support.apple.com/kb/TS1627
3.) Plug in the iOS device and attempt a sync.
--- Check the Info tab in iTunes to make sure calendars are still set to sync.
If that does not resolve the issue let me know and I'll give you a different route.

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