IPhone & iPad sync failure with usbmuxd issues

I've lost all wired connectivity between iPad and iPhone to the paired desktop (never managed to get the wifi sync working) despite using previously working connection via hub and then direct USB cable connection. I have checked that the devices appear within device tree in System Information so it's not likely to be a hardware fault.
iOS devices are running latest 5.0.1 software
Desktop has 10.7.2 running latest iTunes 10.5.1
All software updated
(The same machine has some mixture of software - including Xcode 4.0, 4.1 - so there could be some tricky thing which has occurred at some point during an upgrade path.. - some pretty old drivers lurking.. and there have been a few silent machine crashes which don't yet have an explanation so I don't know if they are related - but there does seem to be a clear issue with recognition of the iDevices by iTunes - Perhaps there is a corrupted driver file?)
What is noticeable and seems new is that when I connect an idevice it starts to spew into the logfile:
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]: usbmuxd-211.2 built on Mar 30 2011 at 18:17:13 on Mar 30 2011 at 18:17:13, running 64 bit
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]: dyld: lazy symbol binding failed: Symbol not found: __PairWithMobileDevice
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]:   Referenced from: /System/Library/PrivateFrameworks/MobileDevice.framework/Versions/A/Resources/u sbmuxd
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]:   Expected in: /System/Library/PrivateFrameworks/MobileDevice.framework/Versions/A/MobileDevic e
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]: dyld: Symbol not found: __PairWithMobileDevice
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]:   Referenced from: /System/Library/PrivateFrameworks/MobileDevice.framework/Versions/A/Resources/u sbmuxd
Nov 30 11:46:23 Picture com.apple.usbmuxd[24208]:   Expected in: /System/Library/PrivateFrameworks/MobileDevice.framework/Versions/A/MobileDevic e
Nov 30 11:46:23 Picture com.apple.launchd[1] (com.apple.usbmuxd[24208]): Job appears to have crashed: Trace/BPT trap: 5
Nov 30 11:46:23 Picture com.apple.launchd[1] (com.apple.usbmuxd): Throttling respawn: Will start in 10 seconds
Nov 30 11:46:23 Picture ReportCrash[24200]: Saved crash report for usbmuxd[24208] version ??? (???) to /Library/Logs/DiagnosticReports/usbmuxd_2011-11-30-114623_localhost.crash
Nov 30 11:46:23 Picture ReportCrash[24200]: Removing excessive log: file://localhost/Library/Logs/DiagnosticReports/usbmuxd_2011-11-30-114251_local host.crash
Seems to me likely that it will be something to do with the daemon or some other machine configuration weirdness - some pointers as to what to do next would be good..
At the moment, when I get back from helping someone else with their IT!, I
am going to set Repair Disk Permissions going (could take a while)
am going to try to find the daemon and compare it with either a TimeMachine version or from a different machine..
any other thoughts? has this been seen anywhere else by someone?
Cheers,
Martin

Steve,
Did you make any progress on this. I have the same situation.

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