Iphone not connecting to itunes on mac

Hi,
I cannot get my iphone to connect to my new imac itunes...when the phone is connect it pops up with a message that there was an invaild response from iphone.
I'm really not sure what else i can do, so far i have made sure....
Itunes is up to date
Iphone is up to date
runnning correct requirements
used all usb ports just incase there was a problem with one
I have also tried a number of different iphone usb cables but they all do the same.
i've always been a windows user and never had a problem with my iphone connecting to itunes.
What else can i do??
Thanks

http://support.apple.com/kb/ts1591

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