IPhone not recognised in iTunes after upgrading to 10.0.1

Hi, I hope someone out there can help with a problem I have with my iPhone 3GS currently running 4.1.
I recently upgraded to iTunes 10.0.1 and iTunes has not worked correctly since.
When I connect my iPhone to PC with a USB I receive the usual pop-up asking what I would like to do with the device, but when I open iTunes, the phone is not located and listed in Devices (devices not even shown on the menu).
I have tried all manner of different things to fix;
Restarted PC
Restarted iPhone
Opened iTunes before connecting phone
Connected phone before starting iTunes
Connected using different USB cables
Used different USB ports
Restarted Apple Mobile Device and iPod Service in Administrative Tools > Services
Uninstalled 10.0.1 and re-installed a previous version of iTunes
After all this, my iPhone is still not being recognised in iTunes.
Can anybody out there help please??
Thanks
Phil

Hi,
Hopefully someone on here might be able to help me also =)
I can't be 100% certain when but pretty sure it's since I updated to itunes 10 I haven't been able to sync or charge my iphone through my laptop, although it still charges through mains charger. My laptop makes a noise when I plug the iphone in but does not recognise it in windows or itunes. I have tried the above steps but cannot locate the phone anywhere in device manager or when in recovery mode. Have tried different cables and usb drives aswell as restarting etc.
Any advice appreciated
Holly

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