IPhone syncing problem with iTunes - 'The iPhone "Leon's iPhone" cannot be synced. An unknown error occurred (-54)

Every time I plug my iPhone into iTunes, it says 'The iPhone "Leon's iPhone" cannot be synced. An unknown error occurred (-54)'. It has never happened to me before until a couple of hours ago!!! So, I decided to totally wipe out my iTunes Library and update it to the latest software. I also updated my iPhone to the latest software (5.1.1.) - and still, even after all this, it still says there is an error and cannot be synced. SERIOULSY APPLE, WHAT NEXT?!!!!! PLEASE HELP!!!!!

I just had the same problem and tried this:
http://support.apple.com/kb/TS1503
Step one worked for me!
Hope this helps.
iPhone 4 iOS 5.1.1 and Windows 7 64-bit

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