Ipod touch isn't acknowledged by itunes and receiving errors.

Pretty sure this has been posted before but all the problems sort of vary.
I have a 2nd generation iPod touch.
When I connect to itunes (I have tried both with itunes open, and connecting and then opening itunes) a popup comes up with either "iTunes could not connect to this iPod because an unknown error occured (0xE8000001)"
OR
"iTunes could not connect to the iPod because an invalid response was received from the device"
I have updated my itunes & ipod to the latest.
I have uninstalled and reinstalled, and restarted the computer.
I have restarted my ipod.
I've worked on the support of the Mobile Device.
The my ipod tab isn't available to click on D:
Like there's no acknowledgment of it being connected.
I don't want know what else to try! I can't put anything new on my ipod it's killing me!
Any help is appreciated (:

I seem to get the 0xe8000001 error fairly consistently on my iPhone 4 (iOS 4.01) the first time I plug it in after booting if I plug it into the computer while the phone is locked... if I unlock the phone so I'm looking at the home screen when I plug it in then that seems to work ok - and lets the phone be seen by iTunes after I've had the error - so it's as if the phone isn't being recognised correctly when it is locked.
It appears to be either a phone or usb driver issue rather than iTunes because when I get the error in iTunes the phone also fails to appear under My Computer in explorer.
Once the phone has been recognised successfully I seem to be able to unplug / replug it without any issues until the next reboot.
Windows 7 Home Premium (64bit), iTunes 9.2

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