Is anyone else having conflict with 10.8.2 update and audio files?

I recently updated from 10.8.1 to 10.8.2 (big mistake).  Now my digital interface has all of these random clicks and pops.  Worse yet, when I try and play my audio files (Digital Performer) or ITUNES that music stops, starts, stutters and is basically unlistenable.  Before the update everything ran smoothly.  I talked with the tech support for my digital music application (Digital Performer) and he thinks there is a conflict with the latest Apple update too.  Is anyone else having these problems?
To get back to 10.8.1 do I have to wipe the hard drive and re-install everything?  I use my Mac for music production so this is killing me.  Any ideas?

I once again reloaded 10.8.2, all of the current firewire, USB, and printer drivers (why not make sure those are up to date too, what have I got to lose?).  Checked the cables, the Mac firewire ports etc.  No change.
So I bought a cheap back up firewire drive (Western Digital, My Passport Studio-about $100).  That worked perfectly on the firewire port of my Mac Pro.
I hooked up my MOTU 828 firewire audio interface into the Western Digital's second firewire port, and everything works perfectly.
I wish I had known that daisey chaining devices would solve my problem before I spent $500 on a new firewire interface.
If you are having similar problems with firewire connection, then try daisey chaining through a device that has no problems.  Who knew a solution could be so simple?

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