Is anyone having issues Updating iTunes and getting message 'itunes64.msi' file missing?

I have been trying to update iTunes 9.2.1.5 to version 10.22 for windows (64bit) and keep getting this message.
Network resource is unavailable. Find an alternate path to a folder containing the installation package. 'itunes64.msi' is not found.
I've been trying to update itunes, so I can update my iPhone4. I've tried installing different versions, same message. I tried uninstalling itunes, and I get the same message! I've searched my computer for this file and cannot find it. I have a Dell XPSM1530 with Windows Vista Service Pack 2.
Does anyone have this problem? I've searched for a solution, but nothing has worked. I also just emailed Apple support about it, we will see what they say.
I would appreciate some help.
Thank you!

Network resource is unavailable. Find an alternate path to a folder containing the installation package. 'itunes64.msi' is not found.
Unfortunately, this sort of trouble has gotten more complicated to deal with ever since Microsoft pulled the Windows Installer CleanUp utility from their Download Center on June 25. First we have to find a copy of the utility.
Let's try Googling. (Best not to use Bing, I think.) Look for a working download site for at least version 3.0 of the Windows Installer CleanUp utility. After downloading the utility installer file (msicuu2.exe), scan the file for malware, just in case. (I use the free version of Malwarebytes AntiMalware to do single-file scans for that.)
If the file is clean, to install the utility, doubleclick the msicuu2.exe file you've downloaded.
Now run the utility ("Start > All Programs > Windows Install Clean Up"). In the list of programs that appears in CleanUp, select any iTunes entries and click "Remove".
Quit out of CleanUp, restart the PC and try installing iTunes again. Does the install go through properly now?
(If you do find a clean download site for the correct version of CleanUp, please don't tell me where it is. Without wishing to sound paranoid (although I grant it does sound paranoid), there is a non-zero chance that posting links to download locations for the utility here at Discussions leads to that download location being shut down.)

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Another oddity that may be associated with the problem: I have a Western Digital 130 gig mass storage unit that I swap between the laptop and the PC as a backup device. The laptop is indicating that the mass storge device is connected when it isn't. The safely remove HW window indicates that the mass storage device and the iPod are connected (but the mass storage device isn't)when I click the safely remove hardware icon. If I close the WD device listing in the remove HW window it shuts down the iPod as well, clears all devices from the window and gives me the message that it is safe to remove the HW. I am beginning to think that this is the root of the evil...any ideas on this point?
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Is anyone having issues Updating iTunes and getting message 'itunes64.msi' file missing?

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