It is not possible to configure the selected XI domain

Hi...
PI 7.0 server on Windows environment and database is SQL Server.
PI Server pick and place the messages from r/3 to r/3 in Oneway but in the reverse it is pick the messages from source but it is not place to the target system.
The error messsage in RWB in end to end monitoring...
It is not possible to configure the selected XI domain because the Integration Server does not exist or could not be read from the SLD
In Component monitoring...
500 internal server error
Application error occured during repuest processing..
Thnx
Raj

Thanks for your promp response, tbluong.
The configuration in SXMB_ADM > Integration Engine Configuration is already done and its check (F7) returns success (all green): "Role of Business System: Current Configuration = System Landscape" and "Corresponding Integration Server: Current Configuration = System Landscape".
Any suggestion?
Regards.

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