ITunes 10.1 only works in Compatibility Mode

I downloaded 10.1 and installed it but when I tried to bring it up the program did not open, A message came up that said it was in XP compatibility mode but still did not work. Uninstalled and reinstalled several times with the same results.
Can anyone help?
Thanks

For general advice see Troubleshooting issues with iTunes for Windows updates.
The steps in the second box are a guide to removing everything related to iTunes and then rebuilding it which is often a good starting point unless the symptoms indicate a more specific approach. Review the other boxes and the list of support documents further down page in case one of them applies.
Your library should be unaffected by these steps but there is backup and recovery advice elsewhere in the user tip.
If you've already done the above and things still aren't working, try opening iTunes in safe mode by holding down CTRL+SHIFT as you launch iTunes, then going into Edit > Preferences > Store and turning off Show iTunes in the Cloud purchases. If you close iTunes and reopen you may find that it now behaves normally.
tt2

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ITunes 10.1 only works in Compatibility Mode

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