Itunes 10.4.1 for mac osx 10.6.8 quits

Ever since I updated itunes I was able to open it once, from then on I cannot open it, it unexpectedly quits during launch. It happens in safe mode as well. This is what I see:
Exception Type:  EXC_BAD_ACCESS (SIGBUS)
Exception Codes: KERN_PROTECTION_FAILURE at 0x000000000000000e
Crashed Thread:  0  Dispatch queue: com.apple.main-thread
Yes, I've re-installed itunes, removed plug-ins, deleted previous versions of quicktime.

Why would you not?
Most never have any issue with an update.  I have never had one, nor has anyone I personally know.
Just as a hospital has many sick people, this technical support forum has many people with issues in need of technical support.  People complain about each and every update.

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