Itunes 10.5 crashes and won't sync my iphone

I have downloaded the software udpate on my Mac Mini that I use to sync my iPhone with.  It offered me an update to iTunes and the iPhone.  I backed up the iPhone and transferred purchases whilst it was downloading the iOS update.  It then updated the phone OS but here is the crunch.  When it then booted the phone iTunes crashes, it won't sync any apps, it won't sync my music, it is as if the phone is new out the box so I have lost all of my settings.
I am not very impressed or very happy.
Also if I now go into iTunes the backup that I took yesterday or previous ones are no longer there so I can't even try a restore to previous backups, they are missing from the list to restore from so I am stuffed.
Any suggestions would be most welcome.

Try the steps in this Apple article -> iTunes: Troubleshooting issues with third-party iTunes plug-ins
Does the error still appear after after removing the plug-ins from the path mentioned below?
/Users/username/Library/iTunes/iTunes Plug-ins/
/Library/iTunes/iTunes Plug-ins/
Is the iPhone recognized correctly after stopping the Eyephedrine plug-in error? And is iTunes now able to connect to the online store?

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