Itunes 10.6.1 (7) incredible slow and sluggish, does anyone know why?

Itunes takes about 5 min to start and when it startes it's unresponsive for another 10 min after that it acts fine. But if I try to connect to itunes store it's the same thing, about 10 min of hang time. Has anyone had a similar experience?
Hardware info:
I don't have itunes match or genius eabled.
os x 10.7.3
  Modellnavn:          MacBook
  Modellidentifikator:          MacBook5,1
  Prosessornavn:          Intel Core 2 Duo
  Prosessorhastighet:          2 GHz
  Antall prosessorer:          1
  Totalt antall kjerner:          2
  Nivå 2-buffer:          3 MB
  Hukommelse:          8 GB
  Busshastighet:          1,07 GHz
  Start-ROM-versjon:          MB51.007D.B03
  SMC-versjon (system):          1.32f8
Library size: 60 Gb give or take
Any help or tips would be apriciated.

Hold down the option key while starting iTunes and tell it to make a new library.  Add a few tracks to the test library. How is response time?
Possible reasons for slowness:
Genius or Match (which you don't have).
Many or highly complex smart playlists.
Huge numbers of regular playlists (some people have been known to make a playlist for each album),
Corrupt library.
Other issue such as file permissions.
In a recent discussion about this somebody found rebuilding their library cured the problem. you can do this but you lose things such are playcount, ratings, date added, playlists, etc.

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