Itunes 10.6 is very slow and rarely plays songs. It will either not show it playing or show it stuck at 0:00

Hey, i have had this problem for a while now and it finally got on my nerves. Itunes has been very slow for me lately and now it rarely even plays a song when i want it too. It either wont register that i clicked the song by freezing up or it will show that the song is stuck at 0:00. Sometimes it does play the song, but i havent figured out why it does at random times and what im doing differently when it does. I have itunes 10.6 on windows 7 64 bit. Any help? That would be great

I have this same issue but on Snow Leopard.  Please help!

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    iMac, OSX 10.6.7, 2.66 GHZ, Intel Core 2Duo, 4GB Ram 1067 MHZ DDR3
    iTunes 10.2.2
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    use other applications but could not click anything in iTunes.
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    OS X automatically defragments files less than 20 MBs in size, so unless you have a disk full of very large files there's little need for defragmenting the hard drive. As for virus protection there are few if any such animals affecting OS X. You can protect the computer easily using the freeware Open Source virus protection software ClamXAV. Personally I would avoid most commercial anti-virus software because of their potential for causing problems. For more about malware see Macintosh Virus Guide.
    I would also recommend downloading a utility such as TinkerTool System, OnyX 2.4.3, or Cocktail 5.1.1 that you can use for periodic maintenance such as removing old log files and archives, clearing caches, etc.
    For emergency repairs install the freeware utility Applejack.  If you cannot start up in OS X, you may be able to start in single-user mode from which you can run Applejack to do a whole set of repair and maintenance routines from the command line.  Note that AppleJack 1.5 is required for Leopard. AppleJack 1.6 is compatible with Snow Leopard. There is no confirmation that this version also works with Lion.
    When you install any new system software or updates be sure to repair the hard drive and permissions beforehand.
    Get an external Firewire drive at least equal in size to the internal hard drive and make (and maintain) a bootable clone/backup. You can make a bootable clone using the Restore option of Disk Utility. You can also make and maintain clones with good backup software. My personal recommendations are (order is not significant):
    Carbon Copy Cloner
    Data Backup
    Deja Vu
    SuperDuper!
    SyncTwoFolders
    Synk Pro
    Synk Standard
    Tri-Backup
    Visit The XLab FAQs and read the FAQs on maintenance, optimization, virus protection, and backup and restore.
    Additional suggestions will be found in Mac Maintenance Quick Assist.
    Referenced software can be found at CNet Downloads or MacUpdate.
    Additional Hints
    Be sure you have an adequate amount of RAM installed for the number of applications you run concurrently. Be sure you leave a minimum of 10% of the hard drive's capacity as free space.
    Add more RAM. If your computer has less than 2 GBs of RAM and you are using OS X Leopard or later, then you can do with more RAM. Snow Leopard and Lion work much better with 4 GBs of RAM than their system minimums. The more concurrent applications you tend to use the more RAM you should have.
    Always maintain at least 15 GBs or 10% of your hard drive's capacity as free space, whichever is greater. OS X is frequently accessing your hard drive, so providing adequate free space will keep things from slowing down.
    Check for applications that may be hogging the CPU:
    Open Activity Monitor in the Utilities folder.  Select All Processes from the Processes dropdown menu.  Click twice on the CPU% column header to display in descending order.  If you find a process using a large amount of CPU time, then select the process and click on the Quit icon in the toolbar.  Click on the Force Quit button to kill the process.  See if that helps.  Be sure to note the name of the runaway process so you can track down the cause of the problem.
    Often this problem occurs because of a corrupted cache or preferences file or an attempt to write to a corrupted log file.

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