ITunes 6 Upgrade - Error -48

I recently had to do a system restore on my computer (Windows XP) and returned it to factory settings, therefore having to reinstall everything including my iPod.
The disc I currently have has an older version of iTunes on it, and when I install it everything works fine, but iTunes tells me to upgrade to 6.1. Without the upgrade I cannot purchase any new music or retrieve the music I had purchased prior to the system restore, which is 100 some songs.
When I try to open iTunes, the iTunes Software Liscence Agreement pops up, I agree, but after that I get an error message that says, "The iTunes application could not be opened. An unknown error occured (-48)." I have tried numerous times to uninstall and reinstall the program, but no luck.
I would do perfectly fine with the older version of iTunes if it weren't for the fact that I, like I said, cannot purchase any new music or get back music I had purchased in the past without this upgrade, and it is really stressing me out.
Hopefully someone here can help me. Thank you if you can.
HP Pavillion F1503   Windows XP  

hi Badgerr!
"The iTunes application could not be opened. An unknown error occured (-48)."
hmmmm. okay, we've been having some weird problems like this (with weird error message numbers like that) being reported when people have their antivirus and antispyware applications either scanning their "My Music" folder or preventing read/write activity in there. (it seems to be to do with the applications interfering with Itunes' ability to interrogate the itunes library files.)
so let's try an experiment, to see if something similar might be happening with your (-48). try disabling your antivirus and/or antispyware packages. will itunes launch properly if you do that?
keep us posted.
love, b

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