ITunes 7.6 (and QuickTime) not opening, error

This is driving me insane, iTunes (from version 7) has never worked on my computer and I feel like I have exhausted every option from support pages. It (and QuickTime) installed successfully but as soon as I try to open either iTunes or QuickTime I simply get the standard malfunctioning message: "iTunes has encountered a problem and needs to close. We are sorry for the inconvenience."
I'd send you the error report, except its huge. Any help would be hugely appreciated, as there is no chance in **** i'm buying an iPod without this sorted. Thanks
Matt

Oh, and I've already checked and tried the FAQ bit..

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