ITunes 7 will not open - Error (-50)

"The iTunes application could not be opened. An unknown error occurred (-50)."
I can't find any information on this specific error anywhere - Anyone have a clue what is going on with this?

and what should i do if i am sitting on 10.3.9 and even not thinking about upgradeing to 10.4.8
are there any more suggestions?
i can't start iTunes for more than a week

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