ITunes freezes after new download and reinstalls.

I have the spinning beach ball of death after iTunes starts for 30 seconds.  I've unsubscribed from podcasts. trashed  my movies.
New variables: new iPad
new version of iTunes 10.6.3 which I have installed twice.  on my MacBook with OS 10. 6.8
I must force quit every time I launch iTunes....
ideas?
It seems to spin when a download starts...
Help please...
Thanks in advance.

I started my computer in SAFE mode and ran REPAIR disc and all is working now.  4 days without iTunes was almost unbearable.  I'm in China, no where near a Genius Bar. 
HELP in the menu bar of Finder   helped me.
Thankfully,
gLj

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