ITunes hangs when phone plugged in

When I try and sync my iPhone to my MacBook, iTunes hangs forcing me to Force Quit the application. I did have an error message about Sync Manager, but found nothing usable about that topic and also an unknown iTunes error 0xe800005e, but again nothing about this topic either.
Can anyone help.

HI and Welcome to Apple Discussions...
Try here. iPhone Basic Troubleshooting
Try a different USB port.
Try deleting this file.
com.apple.PreferenceSync.plist
~/Library/Preferences. Move that file to the Trash.
Make sure you have the lastest version of iTunes. Launch iTunes without the iPhone connected to your Mac. From the Menu Bar, click iTunes/About iTunes. The most recent version is 9.0.1.
If you need to update your iTunes software, from the Menu Bar click iTunes/Check for Updates.
Repair disk permissions.
Quit any open applications/programs. Launch Disk Utility. (Applications/Utilities) Select MacintoshHD in the panel on the left, select the FirstAid tab. Click: Repair Disk Permissions. When it's finished from the Menu Bar, Quit Disk Utility and restart your Mac. If you see a long list of "messages" in the permissions window, it's ok. That can be ignored. As long as you see, "Permissions Repair Complete" when it's finished... you're done. Quit Disk Utility and restart your Mac.
And try Restarting your iPhone.
To restart iPhone, first turn iPhone off by pressing and holding the Sleep/Wake button until a red slider appears. Slide your finger across the slider and iPhone will turn off after a few moments. Next, turn iPhone on by pressing and holding the Sleep/Wake button until the Apple logo appears.
Carolyn
Message was edited by: Carolyn Samit

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