Itunes, have to force quit, will not work since update

After the itunes and quicktime updates, itunes no longer works. After about 10 seconds after launching itunes, it tries to process and then you have to force quit itunes.
any thoughts or suggestions would be greatly appreciated.
Regards
Jim

brookesuk,
Thanks for asking...
A Quick primer
On Macs, the Macintosh HD (or whatever you have renamed it to) icon is on the desktop, right?
So if you open this, you see a Library folder, it is also referred to as /Library
(with the "/" indicating root level, i.e. Macintosh HD)
If you go to your Home folder, it has a Library folder too. It is referred to as ~/Library. (With the "~/" indicating user level)
Now, these steps (taken from KB 25398, section B3), summarize this well:
1. Go to ~/Library
2. Drag the Caches folder to the desktop.
3. Attempt to reproduce the issue.
4. If issue is resolved, drag the Caches folder to the Trash.
5. If issue persists, go to /Library.
6. Drag the Caches folder to the desktop.
7. Attempt to reproduce the issue.
8. If issue is resolved, drag the Caches folder to the Trash
Hope this helps,
Generik
Dual 2.3 GHz PowerPC G5   Mac OS X (10.4.8)  

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