Itunes keeps coming up with Error -43 while backing up to update my iphone...help

I'm trying to update my iphone 4 to iOS 6.1 and it keeps coming up with the message "An error occured while backing up this iphone -43".. it also tells me that if I wish to continue I will lose all content on the phone so I have just been cancelling. I have followed the trouble shooting steps but I still get the same message. Can anyone please help.
Thanks

Let's try a standalone Apple Application Support install. It still might not install, but fingers crossed any error messages will give us a better idea of the underlying cause of the issue.
Download and save a copy of the iTunesSetup.exe (or iTunes64setup.exe) installer file to your hard drive:
http://www.apple.com/itunes/download/
Download and install the free trial version of WinRAR:
http://www.rarlab.com/
Right-click the iTunesSetup.exe (or iTunes64Setup.exe), and select "Extract to iTunesSetup" (or "Extract to iTunes64Setup"). WinRAR will expand the contents of the file into a folder called "iTunesSetup" (or "iTunes64Setup").
Go into the folder and doubleclick the AppleApplicationSupport.msi to do a standalone AAS install.
Does it install properly for you? If so, does iTunes launch properly now?
If instead you get an error message during the install, let us know what it says. (Precise text, please.)

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