ITunes on my iMac seems to think my iPhone is connected and tries to sync even even when it is not.

iTunes on my iMac seems to think my wife's iPhone is connected and tries to sync even even when it is not.  This has been going on for a couple of years now and I am finally trying to stop it. I launch iTunes manually to sync any number of devices we have in the household and, at least every third time I launch iTunes, it pops up my wife's iPhone and start spinning around as if it is connected and syncing but it is not.  This happened to me today when my wife and her iPhone were not even in the house or even the same city for that matter!  Oddly, she recently (finally) upgraded from an iPhone 3 to a 5 assuming that would finally stop it but it just kept on happening.  Anyone have any idea how to stop this?  Thanks!
- Matt

You might start with:
Open Activity Monitor in the Utilities folder.  Select All Processes from the Processes dropdown menu.  Click twice on the CPU% column header to display in descending order.  If you find a process using a large amount of CPU time, then select the process and click on the Quit icon in the toolbar.  Click on the Force Quit button to kill the process.  See if that helps.  Be sure to note the name of the runaway process so you can track down the cause of the problem.
If the above reveals nothing helpful, then create a new user account. Log out of your account and log into the new account. Do the problems cease?

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