Itunes problem Vista

Hi
For some reason Itunes will no longer work on my pc - I am using Windows Vista Home Basic, Version 6.0 (build 6002: Service Pack 2)
I read through the help sections, so far I have deleted the temp folder in appdata (but still doesnt work when i try to reinstall after restarting)
I have also attempted installing the MS utilities but when i install i get this error:
"Error: script: C:\users\MYUSER\AppData\Local\Temp\IXPOOO.tmp\Startmsvbs
Line17 - char1 - error permission denied: CODE 800A0046 Source VB Script runtime error.
If i try and re-install itunes i get this message :-
"A network error occured while attempting to read from the file :
C:\Windows\installer\itunes.msi
Not sure what is going wrong but I am missing listening to my music, please can someone advise me how to solve this??
Thanks Claire

Uninstall both iTunes and Apple Software Update, then reinstall iTunes and the problem should be gone

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