ITunes randomly won't open. HELP PLEASE!!!

I downloaded iTunes when I first bought my laptop and I've been an active user for months, opening it almost everyday. However, a few days ago I go to open it and the mouse would change to say it was loading. Then it would dissapear as fast as it came up. I've tried unistalling and re instaling it. I tried deleting all folders and downloading different bit versions. I have Windows 8, but this hasn't been a probem for the months I've been using it. Although I've been ignoring the request for updating it, that should be no problem when I download the latest version. I've also tried running it as admin and messed with all the different settings. It seems as if it downloads fine, but the second I click on it, it doesn't come up. While troobleshooting and other things a certain setting would be changed so that when I test the program or go to open it again it will ask if it can make changed to my computer. I'll hit yes, but it won't open and that it the only thing that comes up after constantly clicking it. I have several divices linked to my iTunes and I have no idea what to do and no way of syncrnizing my devices. Please help!!!
Oh! And also, it says there is something wrong with the compatibility when troobleshooting, but I've messed with almost all of the settings

Hey Jess,
It sounds like you're already on the right track with your troubleshooting steps, but there are a few more you haven't done listed here:
iTunes for Windows Vista or Windows 7: Troubleshooting unexpected quits, freezes, or launch issues
http://support.apple.com/kb/TS1717
I'd run through the suggested steps in there to see if that resolves the issue.
Have a good one,
Delgadoh

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