Itunes SPOD after latest OS-X Update

I recently installed the latest OS-X updates, and now when I launch iTunes, I get nothing but SPOD and have to kill the iTunes process. I have directly downloaded the latest iTunes application and reinstalled it, still SPOD on launch. I launched iTunes in Safe Mode, still SPOD. I moved the preferences file, still SPOD. I am totally out of ideas here. What else can I do or try to get iTunes to work?

I should add that there are no more pending OS-X updates; I just checked again to be certain.
Furthermore, potentially unrelated, my Internet connection was down for a few days, but has been restored for over 24 hours now. I have seen some iTunes weirdness on forums in relation to that, although I don't suspect that is my issue.
My issue is a lot like the "Upgrade to 10.6.5 + iTunes 10.1 = iTunes stupor" thread in that my iTunes won't see any of my devices either, but he doesn't seem to have the same pinwheel issue. My iTunes is chewing up 22% of the CPU just sitting there until I kill the process from command line.

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