Itunes update cannot install

having trouble installing a new version of itunes on my computer. i keep getting an error that says cannot be installed. try doing it manually, and i did that and the same error popped up. any help would be appreciated.

i got the same error saying that windows installer cannot be accessed.
Do you have a 64-bit version of Vista?
If so, try the instructions from the following document:
Vista Home Premium (x64) and installing Itunes - SOLUTION

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