ITunes will not Launch - System error

After updating my OS X to 10.4.3 and updating iTunes to 6.0.1 I found that I was unable to launch iTunes. The error message stated "unable to read file or write to disk".
This seemed to sound like the file or app was locked down from what I understand from my other mac friends.
I am desperately missing my iTunes music and the ability to view Quicktime as well. Not sure if they are inter-linked.
Somebody please help?
17" Metallic G4 Powerbook Mac OS X (10.4.3)

Put me on the list of people for whom iTunes won't launch anymore.
I got the notification that iTunes had a new upgrade last night. So I let it. After that, everthing seemed to go normally except that after I click to accept the licence agreement, an error comes up
"The iTunes application could not be opened. An unknown error occurred. 0x666D743F"
That's it. I've tried removing iTunes and reinstalling about 4 times. I've also removed both iTunes and Quicktime, then reinstalling. I don't use Norton firewall. I do use Norton Antivirus. NAV is up to date.
I've used the registry editor to check for anything that may be left behind. It appears clean after an uninstall.
An interesting thing is that the desktop icon after a reinstall is a generic looking one with 6 little icons inside a slightly larger rectangle. When I right click to change to the nicer iTunes icon I notice that a lot of information to "start the program in" is missing. I've tried putting the path to iTunes in there, but that doesn't help either.
I sure hope some help or a fix/workaround or whatever is forthcoming. My iPod nano is going to be useless soon without a functioning iTunes.

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http://support.apple.com/kb/HT2311
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I too, could kiss your feet! I had to scrub my work computer, and I can't work without muzak. It was driving me crazy!!!! You have saved me a large amount of sanity.
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ITunes will not Launch - System error

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