ITunes won't run - error message

"iTunes has encountered a problem and needs to close. We are sorry for the inconvenience."
I have tried many suggestions - Turning off Virus protection (McAfee), Running Ad-Aware and Spybot Search and destroy, and even doing a system restore.
Upon trying to do a system restore i noticed that my computer has jumped ahead to the year 2165.
How is this possible? What would cause this?
Also, when i try to update definitions in my spyware programs, the process fails.
I need help. No viruses are detected when i run any programs.

well done uproom_stares!
apologies for the nosy question, but what viruses did the scan pick up?
i've seen cases of W32.Pinfi/Win32.Parite.A cause people vaguely similar sorts of grief:
W32.Pinfi
... but it's not particularly easy to diagnose (from our end of things) because the symptoms aren't tremendously consistent. (i think they might end up depending on what particular .exe files get eaten by a particular infection on a particular machine.)
love, b

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