ITunes wont open (locked disc msg)

The reason Displayed
the Folder "iTunes" is on a locked disk or you do not have write permissions for the folder.
the history
I have had various problems with corrupted library and duplicated song files so i have recent had to manually remove all duplicates directly through finder and attempted to delete all the songs from itunes, keeping files upon request, i have also recently updated one of my internal Hard drives and moved my itunes library to the updated HD which was originally on my external drive, the external drive is now in use as my time machine.
in iTunes i have now only one song left which for some reason will not be deleted although my entire library is intact in finder. after several attempts to delete it, every time crashing iTunes, i attempted to redirect iTunes to its new library location, on the new HD, however iTunes crashed again this time though failing to reload due to the message above
i have tried various things
including turning time machine off
going into file permissions and changing the permissions of "iTunes" / iTunes library" / and about 20% of albums
re installing iTunes
still nothing helps, i believe the fault is probably down to my own doing but i need help to sort out please help!!!

I had the same issue last night(locked library) and had decided to force delete and rebuild the library file later today.
It's a new library so I wasn't worried about losing playlists, but as it would also mean losing my manually placed album artwork (about 100 albums that are not picked up by the automatic 'get album artwork') so wanted to do some more research first.
Thanks for this suggestion. I'll try later and tell you how it goes.
Cheers.

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