Itunes wont open says this:

All of a sudden when i try to open itunes with or without my ipod in it says this "You cannot open the application "itunes" because another user has it open. Ask the other user to quit the application then try again". And no one else in my house has it open and i try to open my brothers itunes and it works. What should I do?

Welcome to discussions! This certainly sounds like you have fast user switching turned on in XP. iTunes & fast user do not play nice together. See the following link.
http://docs.info.apple.com/article.html?artnum=93395

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