Jumpy slow mouse and keyboard that has a mind of its own

Hi Folks
Please bear with me, I am not a computer geek but a mature lady who opted for a mac years ago and now has a mac family!
My current imac is running on OS X 10.5.8, 2.4 GHz Intel Core 2 Duo with 1 GB Memory
Over the past few months if I leave my mac on overnight (as I usually do),  soon enough the mouse starts jumping and is irratic so I find I can't land on anything to open or shut it down.  The keyboard also becomes possessed with a will of its own.
My son was the one who got me onto a mac as he said they don't get viruses (but that was some 12 years ago with my first one).
I did download Mackeeper 2012 which said I was critical at every stage and I tried rectiving it with mackeeper but it said I had done what I could with the free trial version so I was going to pay for it and thought hey.... just check out the reviews etc and because the Mac experts didn't give it a good rating and said it was crap I sent it to trash.
Any ideas on what my problem is and please bear in mind that I'm not an expert, can bake a cake but lost with computers.
Many thanks
Mel

Hello Mel,
I have no idea how they can get away with advertising MacKeeper at all.
You really really need to uninstall it, but not using their uninstaller.
Klaus1's great post on MacKeeper...
https://discussions.apple.com/docs/DOC-3027#comment-2156
More...
https://discussions.apple.com/message/15732233#15732233
https://discussions.apple.com/thread/2779849?start=0&tstart=0
http://applehelpwriter.com/2011/09/21/how-to-uninstall-mackeeper-malware/

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