Lately my Macbook Pro is really slow

Question

My Macbook Pro is unbarebly slow. Launching Safari takes around 55 bounces/seconds. Just opening any app is something I time with making coffee or a bathroom visit, just because it takes forever. At first I was suspecting the HDD, but I've tried multiple softwares to diagnose the discs and no errors are reported. Diagnose softwares reports nothing wrong with my memory sticks either, but that could still be a fail source I guess.
- I've repaired disc permissions
- I've repaired/verified disc
- I've reinstalled OS X
I'm beginning to believe there's something wrong with OS X 10.8 and my older MBP and thinking about downgrading to see if that would help, but that doesn't seem like a sustainable solution to me.
Etrecheck report:
Hardware Information:
          MacBook Pro - model: MacBookPro7,1
          1 2.4 GHz Intel Core 2 Duo CPU: 2 cores
          8 GB RAM
Video Information:
          NVIDIA GeForce 320M - VRAM: 256 MB
System Software:
          OS X 10.8.2 (12C60) - Uptime: 0 days 0:12
Disk Information:
          Hitachi HTS545025B9SA02 disk0 : (250.06 GB)
                    disk0s1 (disk0s1) <not mounted>: 209.7 MB
                    Untitled (disk0s2) /: 249.2 GB (89.34 GB free)
                    Recovery HD (disk0s3) <not mounted>: 650 MB
          HL-DT-ST DVDRW  GS23N 
USB Information:
          Apple Inc. Built-in iSight
          Apple Internal Memory Card Reader
          Apple Inc. BRCM2046 Hub
                    Apple Inc. Bluetooth USB Host Controller
          Apple Computer, Inc. IR Receiver
          Apple Inc. Apple Internal Keyboard / Trackpad
FireWire Information:
Kernel Extensions:
Problem System Launch Daemons:
Problem System Launch Agents:
                 [failed] com.apple.mrt.uiagent.plist
Launch Daemons:
                 [loaded] com.adobe.fpsaud.plist
                 [loaded] com.adobe.SwitchBoard.plist
                 [loaded] com.bresink.system.securityagent3.plist
Launch Agents:
             [not loaded] com.adobe.AAM.Updater-1.0.plist
User Launch Agents:
                 [loaded] com.adobe.AAM.Updater-1.0.plist
                 [loaded] com.google.keystone.agent.plist
User Login Items:
          iTunesHelper
          Dropbox
3rd Party Preference Panes:
          Flash Player
Internet Plug-ins:
          AdobeExManDetect.plugin
          Flash Player.plugin
          FlashPlayer-10.6.plugin
          JavaAppletPlugin.plugin
          QuickTime Plugin.plugin
User Internet Plug-ins:
Bad Fonts:
          None
Top Processes by CPU:
               9%          WebProcess
               4%          Safari
               3%          WindowServer
               2%          EtreCheck
               1%          mds
               0%          fontd
               0%          hidd
               0%          ps
               0%          mdworker
               0%          imagent
Top Processes by Memory:
          311 MB          WebProcess
          98 MB          Safari
          66 MB          Dropbox
          49 MB          mds
          33 MB          Dock
          25 MB          CalendarAgent
          25 MB          SystemUIServer
          25 MB          WindowServer
          16 MB          com.apple.dock.extra
          16 MB          loginwindow

Answer 1

Suggestions for Resolving Slow Downs
If your computer seems to be running slower here are some things you can do:
Start with a visit to: OS X Maintenance - MacAttorney.
Boot into Safe Mode then repair your hard drive and permissions:
Repair the Hard Drive and Permissions Pre-Lion
Boot from your OS X Installer disc. After the installer loads select your language and click on the Continue button. When the menu bar appears select Disk Utility from the Utilities menu. After DU loads select your hard drive entry (mfgr.'s ID and drive size) from the the left side list.  In the DU status area you will see an entry for the S.M.A.R.T. status of the hard drive.  If it does not say "Verified" then the hard drive is failing or failed. (SMART status is not reported on external Firewire or USB drives.) If the drive is "Verified" then select your OS X volume from the list on the left (sub-entry below the drive entry,) click on the First Aid tab, then click on the Repair Disk button. If DU reports any errors that have been fixed, then re-run Repair Disk until no errors are reported. If no errors are reported click on the Repair Permissions button. Wait until the operation completes, then quit DU and return to the installer.
If DU reports errors it cannot fix, then you will need Disk Warrior and/or Tech Tool Pro to repair the drive. If you don't have either of them or if neither of them can fix the drive, then you will need to reformat the drive and reinstall OS X.
Repair the Hard Drive - Lion
Boot from your Lion Recovery HD. When the recovery menu appears select Disk Utility. After DU loads select your hard drive entry (mfgr.'s ID and drive size) from the the left side list.  In the DU status area you will see an entry for the S.M.A.R.T. status of the hard drive.  If it does not say "Verified" then the hard drive is failing or failed. (SMART status is not reported on external Firewire or USB drives.) If the drive is "Verified" then select your OS X volume from the list on the left (sub-entry below the drive entry,) click on the First Aid tab, then click on the Repair Disk button. If DU reports any errors that have been fixed, then re-run Repair Disk until no errors are reported. If no errors are reported, then click on the Repair Permissions button. Wait until the operation completes, then quit DU and return to the main menu. Select Restart from the Apple menu.
Boot to the Recovery HD:
Restart the computer and after the chime press and hold down the COMMAND and R keys until the menu screen appears. Alternatively, restart the computer and after the chime press and hold down the OPTION key until the boot manager screen appears. Select the Recovery HD and click on the downward pointing arrow button.
Restart your computer normally and see if this has helped any. Next do some maintenance:
Suggestions for OS X Maintenance
For situations Disk Utility cannot handle the best third-party utility is Disk Warrior;  DW only fixes problems with the disk directory, but most disk problems are caused by directory corruption; Disk Warrior 4.x is now Intel Mac compatible.
OS X performs certain maintenance functions that are scheduled to occur on a daily, weekly, or monthly period. The maintenance scripts run in the early AM only if the computer is turned on 24/7 (no sleep.) If this isn't the case, then an excellent solution is to download and install a shareware utility such as Macaroni, JAW PseudoAnacron, or Anacron that will automate the maintenance activity regardless of whether the computer is turned off or asleep.  Dependence upon third-party utilities to run the periodic maintenance scripts was significantly reduced since Tiger.  These utilities have limited or no functionality with Snow Leopard or Lion and should not be installed.
OS X automatically defragments files less than 20 MBs in size, so unless you have a disk full of very large files there's little need for defragmenting the hard drive. As for virus protection there are few if any such animals affecting OS X. You can protect the computer easily using the freeware Open Source virus protection software ClamXAV. Personally I would avoid most commercial anti-virus software because of their potential for causing problems. For more about malware see Macintosh Virus Guide.
I would also recommend downloading a utility such as TinkerTool System, OnyX 2.4.3, or Cocktail 5.1.1 that you can use for periodic maintenance such as removing old log files and archives, clearing caches, etc.
For emergency repairs install the freeware utility Applejack.  If you cannot start up in OS X, you may be able to start in single-user mode from which you can run Applejack to do a whole set of repair and maintenance routines from the command line.  Note that AppleJack 1.5 is required for Leopard. AppleJack 1.6 is compatible with Snow Leopard. There is no confirmation that this version also works with Lion.
When you install any new system software or updates be sure to repair the hard drive and permissions beforehand.
Get an external Firewire drive at least equal in size to the internal hard drive and make (and maintain) a bootable clone/backup. You can make a bootable clone using the Restore option of Disk Utility. You can also make and maintain clones with good backup software. My personal recommendations are (order is not significant):
  1. Carbon Copy Cloner
  2. Data Backup
  3. Deja Vu
  4. SuperDuper!
  5. SyncTwoFolders
  6. Synk Pro
  7. Synk Standard
  8. Tri-Backup
Visit The XLab FAQs and read the FAQs on maintenance, optimization, virus protection, and backup and restore.
Additional suggestions will be found in Mac maintenance Quick Assist.
Referenced software can be found at CNet Downloads or MacUpdate.
Additional Hints
Be sure you have an adequate amount of RAM installed for the number of applications you run concurrently. Be sure you leave a minimum of 10% of the hard drive's capacity as free space.
Add more RAM. If your computer has less than 2 GBs of RAM and you are using OS X Leopard or later, then you can do with more RAM. Snow Leopard and Lion work much better with 4 GBs of RAM than their system minimums. The more concurrent applications you tend to use the more RAM you should have.
Always maintain at least 15 GBs or 10% of your hard drive's capacity as free space, whichever is greater. OS X is frequently accessing your hard drive, so providing adequate free space will keep things from slowing down.
Check for applications that may be hogging the CPU:
Open Activity Monitor in the Utilities folder.  Select All Processes from the Processes dropdown menu.  Click twice on the CPU% column header to display in descending order.  If you find a process using a large amount of CPU time, then select the process and click on the Quit icon in the toolbar.  Click on the Force Quit button to kill the process.  See if that helps.  Be sure to note the name of the runaway process so you can track down the cause of the problem.
Often this problem occurs because of a corrupted cache or preferences file or an attempt to write to a corrupted log file.