Lightroom 2.4 - Won't display pictures in preview thumbnail and main panel

I've included a picture so you get what i mean?
I'm currently using lightroom 2.4 which i've upgraded from 2.2 (2.2 actually had this problem so i decided to bite the bullet and upgrade but it didn't help my problem). I tried creating a new catalogue, importing a new photo, syncronising the folders, optimising the catalogue and re-installing lightroom 2.4. I also restored my computer to a couple of days ago. I know it worked a couple of days ago so im not sure exactly whats happening here.
I've opened up other photo editing programs to see if i can view the photos and yes I can.
I know in lightroom when i go to print or web or slideshow it will show the picture but I just don't understand what i can do to resolve this problem. I tried searching on google and its driving me up the wall.
I hope someone knows whats going on here!
Regards
B

sorry Ian and kwdaves. yeah I'm using windows vista on my laptop updated to the latest Service pack (2)
I'll have a look at that faq and having said that. for some reason it was on YCC Profiles? that may have been due to me using a pdfcreator program the other day.. I feel stupid i changed it to adobeRGB (1998) as shown in solution 2 on http://kb2.adobe.com/cps/402/kb402376.html
thanks a lot guys. you both helped immensely and I can actually get a good nights rest.
You guys rock
Regards
B

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