Lightroom 3 does not start after hard drive replacement

I have just recently replaced the hard drive on my IMac. All files and applications have been re-installed from the time machine back up drive. LR shows up on the dock but when I open it it comes up with:
"The Lightroom catalog named “Lightroom 3 Catalog” cannot be opened because another application already has it opened" and "Quit the other copy of Lightroom before trying to launch."
Do I have to reinstall LR3 from the LR DVD? I do not want to use loose the catalog structure and edit info.
Any advise?
Thanks in advance.

Look in the folder that contains your catalog and see if there is a .lock file present. If so, delete it and try again.

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