Lightroom 5 cannot open catalogue

suddenly Lightroom says during launch: "Der Lightroom-Katalog “Fotos” kann nicht geöffnet werden, da er bereits von einer anderen Anwendung geöffnet wurde." "Can not open Lightroom Catalogue "Fotos" because it's used by another Programm" No other App is running. What can I do?!
I use an extern HDD, where my catalogue and the files are stored. Restarting, unmounting the HDDs, nothing works

Go to the folder that contains your catalog file, delete a file whose name ends with .lock
Do not delete any other files

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