Logic stop working while using midi

I have a new Macbook pro with two USB 3.0 ports and  im using a mbox 2 (usb2.0) connect to one of this 3.0 ports. When im playing with my midi keyboard, the midi stop working and my audio interface stop working too after that. Is my USB 3.0 port compatible with my Audio interface(that is USB 2.0) ? What can i do? Thanks for the answer.

Try resetting the iPod first. To reset, press and hold the Sleep/Wake and Home buttons for about 10 seconds (ignore the option to turn off the iPod). If that didn't work, try restoring the iPod. Restoring the iPod will erase the iPod's content, but you can get them back by restoring from a backup. To restore, plug the iPod in your computer. In the main iPod preferences, click restore and follow the instructions.

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