Lync 2013/Office 2010 authentication issues

Hi everyone,
I am fairly new to the OCS/Lync environment and have a question about one of our users. 
He is running Win 7 Ent (x64) and has Office 2010 and Lync 2013 installed (both x86).  It appears that at the most random times, Lync will prompt him to enter his username and password in order for Lync to integrate his Outlook information. 
I have entered his username as domain\username and the correct password and this corrects the issue, but only for a few minutes.  Once Lync prompts him again, almost simultaneously, he gets the Outlook box asking him to verify his credentials. 
When we enter his credentials in the Outlook box, it does not take and the box persistently pops up (of course, this ends up locking out his account but once we unlock it the cycle continues.  I have tried turning outlook cached mode on and off and I
cannot seem to figure out why his credentials are not being accepted.  
I'm not asking for anyone to solve the issue directly; rather, if you have any idea where I can start to read and learn about how these products integrate and what might cause this issue, I'd be very appreciative.  Of course a couple of places to start
troubleshooting would be appreciated and respected as well :)
Thanks everyone!
PS - I posted to Lync 2010 forum because there was not one for Lync 2013. 

I have the same issue, except this variable. 
When adding Lync 2013 to my workstation and another coworkers workstation, neither of us were able to connect to the mail server with Outlook. The login box would appear, but not authenticate. I tried removing my credentials for outlook under the User/Groups
area, but to no avail. The next step was to remove my mail account and re-setup. Outlook will now refuse to take any settings for this email account. Email is hosted in Office 365 solely. The only two systems affected are those with Lync 2013 installed. 
Next step is to remove all traces of Office 2010 and 2013. If this does not resolve the issue, what background authentication piece did I overlook? Were there any authorization changes ordifferences between
2010 and 2013 when it comes to AD/Office 365 integration? 
Thanks,
Charles
EDIT: I removed all traces of Office 2010 as well as registry entries, and reinstalled. Auto discover over AD still isn't working, and now Outlook keeps popping up a dialog box asking for my username and password for the email account. 
Help.

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