Mac Book Pro slow with boot up since Mavericks upgrade

Hi folks,
my mac book pro is booting up very slow and running slow as well since I upgraded to Mavericks.
Tried cleaning up, booting in safe mode, veryfying disk utility but nothing detected.
Can someone check my ETRE or does anyone have another idea what I can do to better the overall performance of my mac?
Thanks and cheers
EtreCheck version: 1.9.11 (43) - report generated 10 June 2014 1:19:56 pm GMT+2
Hardware Information:
          MacBook Pro (15-inch, Mid 2009)
          MacBook Pro - model: MacBookPro5,3
          1 2.66 GHz Intel Core 2 Duo CPU: 2 cores
          4 GB RAM
Video Information:
          NVIDIA GeForce 9400M - VRAM: 256 MB
          NVIDIA GeForce 9600M GT - VRAM: 256 MB
System Software:
          OS X 10.9.3 (13D65) - Uptime: 0 days 0:14:20
Disk Information:
          Hitachi HTS545032B9SA02 disk0 : (320.07 GB)
                    EFI (disk0s1) <not mounted>: 209.7 MB
                    Macintosh HD (disk0s2) / [Startup]: 319.21 GB (91.53 GB free)
                    Recovery HD (disk0s3) <not mounted>: 650 MB
          MATSHITADVD-R   UJ-868
USB Information:
          Apple Inc. Built-in iSight
          Apple Internal Memory Card Reader
          Apple Inc. Apple Internal Keyboard / Trackpad
          Apple Computer, Inc. IR Receiver
          Apple Inc. BRCM2046 Hub
                    Apple Inc. Bluetooth USB Host Controller
Gatekeeper:
          Mac App Store and identified developers
Kernel Extensions:
          [not loaded] com.wdc.driver.1394HP (1.0.11 - SDK 10.4) Support
          [not loaded] com.wdc.driver.1394_64HP (1.0.1 - SDK 10.6) Support
          [not loaded] com.wdc.driver.USBHP (1.0.11) Support
          [not loaded] com.wdc.driver.USB_64HP (1.0.0 - SDK 10.6) Support
Launch Daemons:
          [loaded] com.adobe.fpsaud.plist Support
          [loaded] com.microsoft.office.licensing.helper.plist Support
User Launch Agents:
          [loaded] com.facebook.videochat.[redacted].plist Support
User Login Items:
          Skype
          Dropbox
Internet Plug-ins:
          JavaAppletPlugin: Version: 14.9.0 - SDK 10.7 Check version
          FlashPlayer-10.6: Version: 13.0.0.214 - SDK 10.6 Support
          QuickTime Plugin: Version: 7.7.3
          Flash Player: Version: 13.0.0.214 - SDK 10.6 Outdated! Update
          Default Browser: Version: 537 - SDK 10.9
          SharePointBrowserPlugin: Version: 14.3.6 - SDK 10.6 Support
          Silverlight: Version: 4.0.50826.0 Support
          iPhotoPhotocast: Version: 7.0
Safari Extensions:
          DuckDuckGo: Version: 1.6.1
Audio Plug-ins:
          BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
          AirPlay: Version: 2.0 - SDK 10.9
          AppleAVBAudio: Version: 203.2 - SDK 10.9
          iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins:
          Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
User Internet Plug-ins:
          Picasa: Version: 1.0 Support
3rd Party Preference Panes:
          Flash Player Support
Time Machine:
          Skip System Files: NO
          Auto backup: YES
          Volumes being backed up:
                    Macintosh HD: Disk size: 297.29 GB Disk used: 212.05 GB
          Destinations:
                    My Passport for Mac [Local] (Last used)
                    Total size: 931.16 GB
                    Total number of backups: 2
                    Oldest backup: 2014-05-15 12:51:17 +0000
                    Last backup: 2014-05-30 21:29:41 +0000
                    Size of backup disk: Excellent
                              Backup size 931.16 GB > (Disk size 297.29 GB X 3)
          Time Machine details may not be accurate.
          All volumes being backed up may not be listed.
Top Processes by CPU:
               3%          WindowServer
               3%          Dropbox
               1%          fontd
               0%          com.apple.WebKit.WebContent
               0%          Skype
Top Processes by Memory:
          172 MB          com.apple.WebKit.WebContent
          143 MB          Safari
          82 MB          Skype
          78 MB          Dropbox
          66 MB          mds_stores
Virtual Memory Information:
          1.90 GB          Free RAM
          1.18 GB          Active RAM
          190 MB          Inactive RAM
          495 MB          Wired RAM
          273 MB          Page-ins
          0 B          Page-outs

[not loaded] com.wdc.driver.1394HP (1.0.11 - SDK 10.4) Support
          [not loaded] com.wdc.driver.1394_64HP (1.0.1 - SDK 10.6) Support
          [not loaded] com.wdc.driver.USBHP (1.0.11) Support
          [not loaded] com.wdc.driver.USB_64HP (1.0.0 - SDK 10.6) Support
Western Digital Software and Mavericks
Remove the software.
Activity Monitor - Mavericks
Activity Monitor in Mavericks has significant changes
Performance Guide
Why is my computer slow
Why your Mac runs slower than it should
Slow Mac After Mavericks
Things you can do to resolve slowdowns see post by Kappy

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