Mac mail 4.5 won't open now 10.6.8 combo update installed

I have been having problems updating software and it was suggested that I installed the 10.6.8 combo update, this i have done and since then my mac mail 4.5 won't open - 'you can't use this version of Mail with this version of Mac OS X ' message!!
What is the simplest way of resolving this problem please?
Thanks
Julie

Hello, just ran accross your query.
Was Mail ever moved out of the Applications folder?
http://support.apple.com/kb/TS4424?viewlocale=en_US&locale=en_US

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