Mac pro losing internal drives after GPU upgrade

I've recently added a PC style 3GB graphics card (NVIDIA GeForce GTX 660) to my early 2008 8 core mac pro.
Apart from living without the boot logo, this has worked very nicely...
But since then I've had some clicking/chirping noises, especially when running graphics intensive apps (e.g. Video editing, some 3D heavy games), and have subsequently lost one of my four internal drives (my iTunes media library), and another drive regularly 'ejects' during these periods.
Is this liable to just be drives failing, or possibly a psu issue, to do with powering this new card?
Has anyone else had issues running 4 internal drives, with a video card like this?
Any thoughts/suggestions would be welcome, thanks!

Beg your pardon, I've just checked again, and the card does just use a 6pin connector. Sorry got confused.
The card lists its minimum requirements as a 450W psu with min 24 amps on the +12V rail (based on i7 3.2 machine)
Does that narrow things down at all? For the record, with only 2 drives mounted at the moment, I still get the odd click from the machine when under some graphics load. Thanks for the replies.

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