Macbook Pro on 10.6.8 won't boot, Help!

I have a 2007 Macbook Pro 2.4ghz Core 2 Duo with 4 gigs of Ram that was running just fine until I left for a weekend away.  When I got home and tried to boot it up it gave me the "universal stop sign" circle with line thru it and wouldn't boot past that screen.  I had problems with the Ram going bad before so I tried putting the stock Ram in it but nothing different happened.  I tried rebooting my pram and also booting in safe mode, none of which worked.  I had a disk of 10.6.3 and am able to boot from that.  I went to disk utility from the DVD which when I tried to verify it it said that I had an issue that needed to be repaired.  I ran the repairs and while it said it fixed them when I verify it again it still says that It needs to be repaired.  So basically i've come to the conclusion that I either need to erase my harddrive and reinstall or maybe someone from this forum can help. 
If I need to reinstall I guess thats what i'll have to do but my questions are as follows:
1.  Since I have the DVD of  10.6.3 do I need to do a fresh reinstall of that and then do all the system updates to get me back to 10.6.8 BEFORE I do my Time Machine restore?  Or can I restore from Time Machine when its still at 10.6.3?
2.  If I restore from Timemachine will it also restore all my Apps?  Or do I need to reinstall them from my disks and the things I purchased from the internet? (I hope not!!)
3.  I noticed an option when I booted from 10.6.3 DVD that you can restore from a Time machine backup... will that fix the issues that my computer is having with trying to boot up or not?  If I try this option and it doesn't work is that going to mess up my Time Machine backup or will it not effect that? 
Sorry for all the questions but I hope someone can enlighten me on these issues.  Thanks

Just to add a little more info to the story I had upgraded my Hard drive from a 5400 RPM 250gig model that came with the computer to one that was made by Seagate and installed in 2011, 7200 RPM 750 gigs.  Is it normal to fail after not even 2 years?
When I try to repair the Disk using Disk Repair I get the Error Message "Invalid content in Journal."  Can anyone enlighten me to what this means?  Trying to repair the disk does not resolve this issue.
Also trying to start in single user mode and run fsck failed and I got a bunch of error messages that ran on a continuous loop. 

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