Macbook running incredibly slow - Etre Info - Please Help!

Question

My Macbook has been running slow for quite sometime, and regardless of my internet provider, it is deathly slow to load.  I have seen individuals post the Etre info, so I thought I would do the same.  Not sure if this will help, but here's hoping!  I understand this computer is quite old, just trying to get it back into fighting shape post college.  Whether it is a hardware upgrade (if possible) or some software tweaks I'm fine with that. Thank you for the help in advance!
Anyone have any ideas?
EtreCheck version: 1.9.12 (48)
Report generated June 19, 2014 at 10:51:49 PM EDT
Hardware Information:
  MacBook Intel Core 2 Duo (white, Late 2009)
  MacBook - model: MacBook6,1
  1 2.26 GHz Intel Core 2 Duo CPU: 2 cores
  4 GB RAM
Video Information:
  NVIDIA GeForce 9400M - VRAM: 256 MB
  Color LCD 1280 x 800
System Software:
  OS X 10.9.3 (13D65) - Uptime: 24 days 0:1:23
Disk Information:
  Hitachi HTS545050B9SA02 disk0 : (500.11 GB)
  EFI (disk0s1) <not mounted>: 209.7 MB
  Macintosh HD (disk0s2) / [Startup]: 499.25 GB (196.58 GB free)
  Recovery HD (disk0s3) <not mounted>: 650 MB
  MATSHITADVD-R   UJ-898
USB Information:
  Apple Inc. Built-in iSight
  Apple Inc. Apple Internal Keyboard / Trackpad
  Apple Inc. BRCM2070 Hub
  Apple Inc. Bluetooth USB Host Controller
Gatekeeper:
  Mac App Store and identified developers
Kernel Extensions:
  [not loaded] com.FTDI.driver.FTDIUSBSerialDriver (2.2.16) Support
Launch Daemons:
  [loaded] com.adobe.fpsaud.plist Support
  [loaded] com.microsoft.office.licensing.helper.plist Support
Launch Agents:
  [loaded] com.hp.messagecenter.launcher.plist Support
User Launch Agents:
  [loaded] com.google.keystone.agent.plist Support
User Login Items:
  iTunesHelper
  Google Chrome
Internet Plug-ins:
  FlashPlayer-10.6: Version: 13.0.0.214 - SDK 10.6 Support
  QuickTime Plugin: Version: 7.7.3
  Flash Player: Version: 13.0.0.214 - SDK 10.6 Cannot contact Adobe
  Default Browser: Version: 537 - SDK 10.9
  SharePointBrowserPlugin: Version: 14.3.9 - SDK 10.6 Support
  Silverlight: Version: 5.1.30317.0 - SDK 10.6 Support
  DirectorShockwave: Version: 11.5.9r615 Support
  iPhotoPhotocast: Version: 7.0
Safari Extensions:
  Yontoo: Version: 1.0
Audio Plug-ins:
  BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
  AirPlay: Version: 2.0 - SDK 10.9
  AppleAVBAudio: Version: 203.2 - SDK 10.9
  iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins:
  Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
User Internet Plug-ins:
  Google Earth Web Plug-in: Version: 7.1 Support
3rd Party Preference Panes:
  Flash Player  Support
  MacFUSE  Support
Time Machine:
  Skip System Files: NO
  Auto backup: YES
  Volumes being backed up:
  Macintosh HD: Disk size: 464.96 GB Disk used: 281.88 GB
  Destinations:
  Time Machine Backups [Local] (Last used)
  Total size: 698.32 GB
  Total number of backups: 28
  Oldest backup: 2010-05-27 22:22:03 +0000
  Last backup: 2014-06-18 23:20:19 +0000
  Size of backup disk: Too small
  Backup size 698.32 GB < (Disk used 281.88 GB X 3)
  Time Machine details may not be accurate.
  All volumes being backed up may not be listed.
Top Processes by CPU:
      10% WindowServer
      10% helpd
      9% Google Chrome
      2% HelpViewer
      0% SystemUIServer
Top Processes by Memory:
  143 MB softwareupdated
  106 MB mds_stores
  98 MB Google Chrome
  94 MB Finder
  94 MB com.apple.IconServicesAgent
Virtual Memory Information:
  243 MB Free RAM
  1.74 GB Active RAM
  1.03 GB Inactive RAM
  561 MB Wired RAM
  6.16 GB Page-ins
  360 MB Page-outs

Answer 1

"Uptime: 24 days 0:1:23": You should restart your computer. If you don't restart it more often, it will get slower.