Macbookpro mail won't quit or open cannot shut down

macbookpro mail wont quit or open and cannot shut down computer help?  my ipad is ok

Hi elizabeth,
Hold down the power button for 5-10 seconds to shut down, then try again.

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    Choose Force Quit from the Apple menu, select that application, and press the Force Quit button. If that doesn't work, save and close everything you can and use the Activity Monitor in the /Applications/Utilities/ folder to force quit the loginwindow process.
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    Same issue here.  15 MBP Retina Late 2012.  MacOS 10.9 and have installed the Mail Update for Mavericks to no avail.
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    Try:
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