Mail error msg - can't open Mail program.

When I click on the Mail icon I get an error message that reads (in part) "...Mail cannot update your mailboxes because your home directory is full."
I've run Disk Utility permissions repair, Disk Warrior, and Tech Tools 4. I've restarted the computer, zapping the pram as I restrted. I've used the reset botton on the motherboard. I've replaced the Mail prefs, and I've junked some old emails from Users/Library/Mail/Mailboxes to reduce the load. Sometime recently (over the past few days), I've run the OSX 10.4.4 update.
Do ya think if I write a nice lette to Steve he'll send me a new Intel/Mac, or should I simply empty an AK47 magazine at my od Mac and use my Dell from now on - a fate way worse than death!
Help (please). Save me, 'cause I'm going down for the 3rd time...
Da Kid
G4 867   Mac OS X (10.4.4)   (3) partitions, (2) 250 gig internal HDs

Do you use Bridge?  If so will they display thumnails?  If so image is probably OK.  Double click on it and it should open in PS.  If not what happens?

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    Ok did some research - here is another thread which seems to address your problem.
    https://discussions.apple.com/message/19019703#19019703
    Try this and let us know how you go.

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    If that works, you need check this registry path to see if it points a right path to the .cpl file:
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    Alex Zhao
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