Mail keeps freezing. Tried loads, nothing has worked. Please HELP!

Hi, My wife has an iBook and on recently updating to 10.5.8 we are having problems with the mail.
I can open Mail and it starts to download but on email number 41 mail freezes and stops downloading.
I have been through the forums and have tried the following:
Firstly i deleted email from the server thinking that email number 41 was the culprit. This didn't work.
Checked what email was important, replied to that, then completely cleared the server of every email! This didn't work.
Set up my wife's email account in mail on my iMac running 10.5.8. Email's dowloaded fine.
Checked the email preferences and they duplicated what was on my iMac exactly but it still kept freezing.
deleted the com.apple.mail.plist set up the account from scratch. this didn't work
Tried rebuilding the mailbox. This didn't work.
Repaired the disk permissions. This didn't work.
Set up a different user on my wife's computer. Set up the email account. This worked!!!!
Copied the com.apple.mail.plist from the new user to the original user. This didn't work.
Any ideas what next?
I have therefore isolated the problem to my wife's account - not the server, corrupted email, computer or system update.
What's left to try? Please help!

Not having had much luck on the forum i contacted apple support direct and they sorted the problem.
1 file and one folder needed to be deleted.
Delete the com.apple.mail.plist found here - Home/library/preferences/
Delete the mail folder found here - Home/library/
then restart the computer. Set up mail from the start and hey presto - no problems.
This suggests that my problem lay in the mail folder and there was a corrupt file somewhere.
***Please note in doing this you will loose every mail setting and email/attachment etc. so save/backup anything that is important to you. Also make sure you have your account information saved as this is lost too!*****
I have seen many threads on this problem and this is the first time i have come across the advice to delete the whole folder. I hope this helps.

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