Make Acrobat the default reader for pdf-files.

Since some time (probably after I installed Mavericks) pdf-files are by default opened
in Preview. To open them in Adobe Acrobat, I can right-click the pdf-file, choose Acrobat,
and indicate that Acrobat should be the default reader for pdf-files.
This works, and after logout and login, it does still work.
But after a reboot, Preview is again the default reader.
Also, if in Finder I right-click a pdf-file, and via Get Info I configure Acrobat
to be the default reader for the specific file and all other pdf-files (by clicking
Change All), this only works for the current session. After a reboot Preview again is the
default.
How can I make Acrobat Reader the default reader for pdf-files, and make this setting
permanent?
Where is this setting saved?
Regards,
Kees.

I finally solved this, but I still don't understand how.
To begin with I have 2 hard-drives in my iMac. The OS is on the primary HD, and data are on the secondary drive. My Home directory too is on this secondary HD.
To check whether the location of the Home directory might be the problem, I copied the Home directory to the primary HD, changed the path in my profile, and did a reboot.
The next step was to configure Adobe Acrobat as the default reader for pdf-files. To my surprise,  after rebooting, Acrobat still was the default reader for pdf-files.
So it looks as if this problem has something to do with the location of the Home directory.
The original Home directory was still present on the secondary  HD,  So the next step was to change in my profile the path to the Home directory again (pointing again to the original Home directory on the second HD), do a reboot and delete the copy of the Home directory on the primary HD.
So now the situation was back to as it was before: the Home directory on the second HD.
To my surprise now Acrobat still was the default reader for pdf-files.
And I could also change the default reader to Preview, and back to Acrobat, and this setting was saved across reboots.
I'm curious to what solved this problem, and where the setting of the default pdf-reader, or more general, the default application for file types, is stored.
So I hope that someone who reads this, can shed some light on this.

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