Microsoft Outlook 2010 very slow start up

Hello there,
Whenever I log on to my Computer and open my Outlook - it takes forever to start up, it's always slow on the 'Loading profile' part. Takes about 10 mins sometimes. However this only happens when I first switch on my Computer - if I close down outlook
and open it again then it loads fine, however if I were to shut down my computer and open it again - then the slow load up process would happen all over again. We currently use Microsoft exchange for our emails. And my outlook has two profiles but only uses
one of them. Should I perhaps delete both profiles and create a new one? I've disabled plugins but that doesn't seem to be the problem. Any ideas?
Many thanks,
Michael Peters

Hi Michael,
Please run Outlook under the safe mode to avoid some AVs and add-ins for testing.
If it works under the safe mode, it seems some AVs or add-ins lead this issue. Please disable them properly.
Please re-create profile to refresh the caches for testing.
Also found some similar thread for your reference:
Outlook 2010 is taking forever to open and load,
http://answers.microsoft.com/en-us/office/forum/office_2010-outlook/outlook-2010-is-taking-forever-to-open-and-load/c4efcd45-ed61-4a97-9178-b1f1c02ca1e2
Outlook 2010 stuck on loading profile
http://answers.microsoft.com/en-us/office/forum/office_2010-outlook/outlook-2010-stuck-on-loading-profile/4ae77263-3173-4ac7-9758-e4483b16a45a
Hope it is helpful
Thanks
Mavis
Mavis Huang
TechNet Community Support

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