Mouse buttons and keyboard randomly stop responding on secondary display

Hey,
I'm facing this weird problem after a recent upgrade to Snow Leopard:
In about half of the cases I'm switching to application windows on a secondary/external display the mouse buttons and Macbook keyboard are unresponsive. I have to keep clicking/pressing for some time or have to switch between applications to get them working, until they'll fail again after some time.
I tested it with two different external displays with VGA and DVI adapter, different screen resolutions, I tested the mouse and mouse software, both keyboard and mouse work fine with the same applications moved to the primary laptop screen, trackpad works fine too.
This occurred after the upgrade to Snow Leopard on a 2008 unibody Macbook. Updates to 10.6.2 didn't solve the problem.
I'd be happy if anyone could help me with this issue.
Thanks

You do not provide the full model number but if it is an AMD processor you are seeing the start of video issues that plague that series. The freeze is caused by bad video memory which is a part of the video card in turn part of the motherboard. I have been getting a high percentage of people who do not respond back to posts so I am not going to write everything about your issue; it could be a book. I am happy to help further if you have any questions. There are some repair options but at the end of the day, you might want to consider a new laptop.

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