Mouse doesn't click what's onscreen in Windows 7 Large Text format

This is an odd issue we've discovered. We are using Windows 7 Enterprise, and a few of my coworkers have changed screen resolution to LARGE text (Right click desktop > Screen Resolution > Make text and other items larger or smaller > Larger - 150% > Apply). When they do this and attempt to use InDesign CS5.5 (7.5.1), their mouse is essentially useless within InDesign. When they click on something within the application, it either doesn't respond at all or does something different. What we've deduced is that it's showing a visual-only larger version of the interface, but the mouse itself is still clicking through a smaller text version of the application that our eyes cannot see. This only occurs with InDesign - not Illustrator or Photoshop.
Has anybody come across this, and if so, any workarounds?

Thanks, Peter. I did check the Adobe page for known bugs and either glossed over this one or it wasn't there. In any case, setting Windows 7 to operate 'Best for performance' turned off all the bells & whistles and now InDesign works fine. It tested the individual settings and it turns out that selecting 'Use visual styles on windows and buttons' is what makes things wonky. Thanks for the tip!

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